
FKBP12 PROTAC dTAG-7
CAS No. 2064175-32-0
FKBP12 PROTAC dTAG-7( dTAG-7 )
Catalog No. M13208 CAS No. 2064175-32-0
FKBP12 PROTAC dTAG-7 (dTAG-7) is a cell-permeable heterobifunctional adation tag (dTAG) small molecule that engage FKBP12F36V and CRBN.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 212 | Get Quote |
![]() ![]() |
5MG | 336 | Get Quote |
![]() ![]() |
100MG | Get Quote | Get Quote |
![]() ![]() |
200MG | Get Quote | Get Quote |
![]() ![]() |
500MG | Get Quote | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product NameFKBP12 PROTAC dTAG-7
-
NoteResearch use only, not for human use.
-
Brief DescriptionFKBP12 PROTAC dTAG-7 (dTAG-7) is a cell-permeable heterobifunctional adation tag (dTAG) small molecule that engage FKBP12F36V and CRBN.
-
DescriptionFKBP12 PROTAC dTAG-7 (dTAG-7) is a cell-permeable heterobifunctional adation tag (dTAG) small molecule that engage FKBP12F36V and CRBN, selectively degrade FKBP12F36V in a CRBN-dependent manner in cells; causes rapid degradation of nuclear and cytoplasmic FKBP12F36V fusion chimeras.
-
In Vitro——
-
In Vivo——
-
SynonymsdTAG-7
-
PathwayPROTACs
-
TargetPROTAC
-
RecptorPROTAC
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2064175-32-0
-
Formula Weight1210.341
-
Molecular FormulaC63H79N5O19
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 150 mg/mL (123.93 mM)
-
SMILESCCC(C1=CC(=C(C(=C1)OC)OC)OC)C(=O)N2CCCCC2C(=O)OC(CCC3=CC(=C(C=C3)OC)OC)C4=CC=CC=C4OCC(=O)NCCCOCCOCCOCCCNC(=O)COC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O
-
Chemical Name(1R)-3-(3,4-dimethoxyphenyl)-1-(2-((19-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-2,18-dioxo-7,10,13-trioxa-3,17-diazanonadecyl)oxy)phenyl)propyl (2S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Nabet B, et al. Nat Chem Biol. 2018 May;14(5):431-441.
molnova catalog



related products
-
dBET1
dBET1 is a proteolysis-targeting chimera (PROTAC) molecule that appendes a competitive antagonist of BET bromodomain (JQ1) to a phthalimide moiety to hijack the cereblon E3 ubiquitin ligase complex.
-
TAMRA-PEG3-Azide
TAMRA-PEG3-Azide is a TAMRA red fluorescent dye linker with a maximum excitation/emission wavelength of 553/575 nm.
-
Gefitinib-based PROT...
Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7 nM and 22.3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R).